A few weeks back, I wrote DropHere. Its written using CoffeeScript, Node.js and Express.js and some HTML5 Drag and Drop APIs.
I created this project as a simple drag-and-drop file uploading service. It uploads files to relevant file uploading service. For example, if you drop an image file, it will be uploaded to Imgur and similarly text files will be uploaded to Pastebin.
You can check out the live demo over here.